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Cholesterol.
Cholesterol is a substance made by the liver and intestines from fatty food that has been consumed. It forms the outer layer of cells and is needed by the body to insulate nerve fibres and make hormones and bile acids that absorb fats. Although cholesterol is vital to ensure that the body functions as it should, there are good and bad types.
Cholesterol is carried around the body by molecules called lipoproteins of which there are three main types. Low-density lipoprotein is known as the bad cholesterol and carries cholesterol from the liver to the cells. If there is more cholesterol than the cells need however, this can cause a harmful build-up, which can eventually lead to disease of the arteries. Known as the good cholesterol, high-density lipoprotein carries cholesterol back to the liver and away from the cells where it is broken down and eventually passed through the body.
Finally, triglycerides come from fatty foods and are used for energy. Whatever is not used is stored in the fatty tissues of the body, however excess triglycerides can increase the chance of heart problems.
It has been recommended that the healthy level of total cholesterol is less than 5.0mmol/L. Levels are measured with a blood test but deciding whether a person has dangerous levels of cholesterol depends on their overall risk of developing heart disease. This overall risk is determined by a range of factors, such as unhealthy eating, being overweight, smoking, high blood pressure, diabetes, as well as a family history of strokes and heart disease.
The risk of coronary heart disease increases as cholesterol levels rise and high levels can lead to narrowing of the arteries, heart attack and stroke. A person may also have high cholesterol because they have an inherited problem called familial hyperlipidaemia.
Treatments for high cholesterol include regular exercise and healthy eating by reducing the intake of trans fats and replacing saturated fats with unsaturated alternatives. Cutting down on foods that are high in saturated fat, such as butter, hard cheese, fatty meat, cream, cake and biscuits and increasing the intake of fruit, vegetables and fibre can actually lower cholesterol levels.
Once steps to reduce cholesterol levels have been taken, lipid-lowering medication can also be used. Popular treatments include Zetia a lipid-lowering compound that selectively inhibits the intestinal absorption of cholesterol – and Mevacor, an inhibitor used to lower cholesterol and triglyceride levels in the blood.
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